Comparison of Brain Transcriptome Profiles of Short-lived and Long-lived Species of Nothobranchius

Zulfiia Guvatova¹, George Krasnov², Sergey Simanovsky³, Alexander Frolov⁴, Nataliya Gladysh⁵, Anna Kudryavtseva^6
1Center for Precision Genome Editing and Genetic Technologies for Biomedicine Engelhardt Institute of Molecular Biology, Russian Academy of Sciences Moscow, Russia, guvatova.zulfiya@mail.ru
²Center for Precision Genome Editing and Genetic Technologies for Biomedicine Engelhardt Institute of Molecular Biology, Russian Academy of Sciences Moscow, Russia, gskrasnov@mail.ru
³Laboratory for Ecological Monitoring of Nuclear Power Plant (NPP) Regions and Bioindication Russia A.N. Severtsov Institute of Ecology and Evolution Moscow, Russia, sergey.a.simanovsky@gmail.com
⁴Laboratory for Ecological Monitoring of Nuclear Power Plant (NPP) Regions and Bioindication Russia A.N. Severtsov Institute of Ecology and Evolution Moscow, Russia, frolov@mail.ru
⁵Veterinary biology faculty MSAVM&B – MVA named after K.I. Skryabin Moscow, Russia, natalyagladish@gmail.com
⁶Center for Precision Genome Editing and Genetic Technologies for Biomedicine Engelhardt Institute of Molecular Biology, Russian Academy of Sciences Moscow, Russia, rhizamoeba@mail.ru

Annual fishes of the genus Nothobranchius from East Africa are promising vertebrate model in comparative and ageing studies. Nothobranchius show accelerated growth and age-related changes at all levels of organization. The present work aims to compare brain transcriptome profiles of short-lived N. rachovii with longer-lived N. korthausae and N. guntheri.