{"id":10123,"date":"2020-06-29T09:36:52","date_gmt":"2020-06-29T09:36:52","guid":{"rendered":"https:\/\/bgrssb.icgbio.ru\/2020\/2020\/06\/29\/differentially-expressed-micrornas-in-carotid-paraganglioma\/"},"modified":"2020-06-29T09:36:52","modified_gmt":"2020-06-29T09:36:52","slug":"differentially-expressed-micrornas-in-carotid-paraganglioma","status":"publish","type":"post","link":"https:\/\/bgrssb.icgbio.ru\/2020\/2020\/06\/29\/differentially-expressed-micrornas-in-carotid-paraganglioma\/","title":{"rendered":"Differentially expressed microRNAs in carotid paraganglioma"},"content":{"rendered":"<p>Anastasiya Snezhkina<sup>1<\/sup>, Elena Pudova<sup>2<\/sup>, Vladislav Pavlov<sup>3<\/sup>, Maria Fedorova<sup>4<\/sup>, George Krasnov<sup>5<\/sup>, Anna Kudryavtseva<sup>6<\/sup><br \/><sup>1<\/sup>EIMB RAS, Moscow, Russia, leftger@rambler.ru<br \/><sup>2<\/sup>EIMB RAS, Moscow, Russia, pudova_elena@inbox.ru<br \/><sup>3<\/sup>EIMB RAS, Moscow, Russia, vladislav1pavlov@gmail.com<br \/><sup>4<\/sup>EIMB RAS, Moscow, Russia, fedorowams@yandex.ru<br \/><sup>5<\/sup>EIMB RAS, Moscow, Russia, gskrasnov@mail.ru<br \/><sup>6<\/sup>EIMB RAS, Moscow, Russia, rhizamoeba@mail.ru<\/p>\n<p><em>Molecular mechanisms underlying the formation of rare tumors are insufficiently known. It the work, we performed the analysis of microRNA profiles in a rare neuroendocrine tumor of the head and neck, carotid paraganglioma (CPGL). We found four microRNAs (miR-1185-1\/2-3p, miR-431-5p, miR-504-5p, and miR-200c-3p) that are differentially expressed among CPGL samples studied. This is the first study of microRNA expression in CPGL. Obtained results allow a better understanding of molecular changes associated with the development of the tumor. <\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anastasiya Snezhkina1, Elena Pudova2, Vladislav Pavlov3, Maria Fedorova4, George Krasnov5, Anna Kudryavtseva61EIMB RAS, Moscow, Russia, leftger@rambler.ru2EIMB RAS, Moscow, Russia, pudova_elena@inbox.ru3EIMB RAS, Moscow, Russia, vladislav1pavlov@gmail.com4EIMB RAS, Moscow, Russia, fedorowams@yandex.ru5EIMB RAS, Moscow, Russia, gskrasnov@mail.ru6EIMB RAS, Moscow, Russia, rhizamoeba@mail.ru Molecular mechanisms underlying the formation of rare tumors are insufficiently known. It the work, we performed the analysis of microRNA profiles in a rare neuroendocrine tumor of the head and neck, carotid paraganglioma (CPGL). We found four microRNAs (miR-1185-1\/2-3p, miR-431-5p, miR-504-5p, and miR-200c-3p) that are differentially expressed among CPGL samples studied. This is the first study of microRNA expression in CPGL. Obtained results allow a better understanding of molecular changes associated with the development of the tumor.<\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2171],"tags":[1605,1606,1607],"_links":{"self":[{"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/posts\/10123"}],"collection":[{"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/comments?post=10123"}],"version-history":[{"count":0,"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/posts\/10123\/revisions"}],"wp:attachment":[{"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/media?parent=10123"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/categories?post=10123"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/tags?post=10123"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}