{"id":10187,"date":"2020-06-29T09:36:52","date_gmt":"2020-06-29T09:36:52","guid":{"rendered":"https:\/\/bgrssb.icgbio.ru\/2020\/2020\/06\/29\/associations-of-polymorphic-variants-of-the-genes-of-neurotrophic-factors-bdnf-ngf-nrg1-with-remission-in-patients-with-depressive-disorders\/"},"modified":"2020-06-29T09:36:52","modified_gmt":"2020-06-29T09:36:52","slug":"associations-of-polymorphic-variants-of-the-genes-of-neurotrophic-factors-bdnf-ngf-nrg1-with-remission-in-patients-with-depressive-disorders","status":"publish","type":"post","link":"https:\/\/bgrssb.icgbio.ru\/2020\/2020\/06\/29\/associations-of-polymorphic-variants-of-the-genes-of-neurotrophic-factors-bdnf-ngf-nrg1-with-remission-in-patients-with-depressive-disorders\/","title":{"rendered":"Associations of polymorphic variants of the genes of neurotrophic factors BDNF, NGF, NRG1 with remission in patients with depressive disorders"},"content":{"rendered":"<p>Natalia Vyalova<sup>1<\/sup>, German Simutkin<sup>2<\/sup>, Nikolay Bokhan<sup>3<\/sup>, Svetlana Ivanova<sup>4<\/sup><br \/><sup>1<\/sup>Mental Health Research Institute of the Federal State Budget Scientific Institution \\&#8221;Tomsk National Research Medical Center of the Russian Academy of Sciences\\&#8221;, Natarakitina@yandex.ru<br \/><sup>2<\/sup>Mental Health Research Institute of the Federal State Budget Scientific Institution \\&#8221;Tomsk National Research Medical Center of the Russian Academy of Sciences\\&#8221;, ggsimutkin@gmail.com<br \/><sup>3<\/sup>Mental Health Research Institute of the Federal State Budget Scientific Institution \\&#8221;Tomsk National Research Medical Center of the Russian Academy of Sciences\\&#8221;, bna909@gmail.com<br \/><sup>4<\/sup>Mental Health Research Institute of the Federal State Budget Scientific Institution \\&#8221;Tomsk National Research Medical Center of the Russian Academy of Sciences\\&#8221;, ivanovaniipz@gmail.com<\/p>\n<p>The investigation the relationship between <em>BDNF, NGF<\/em> and <em>NRG1<\/em> genotypes with remission in patients with MDD was made in a group of 208 patients. The study showed that rs3924999 of the <em>NRG1<\/em> gene was associated with clinical remission, rated on the HDRS-17 scale on day 28 of antidepressant therapy.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Natalia Vyalova1, German Simutkin2, Nikolay Bokhan3, Svetlana Ivanova41Mental Health Research Institute of the Federal State Budget Scientific Institution \\&#8221;Tomsk National Research Medical Center of the Russian Academy of Sciences\\&#8221;, Natarakitina@yandex.ru2Mental Health Research Institute of the Federal State Budget Scientific Institution \\&#8221;Tomsk National Research Medical Center of the Russian Academy of Sciences\\&#8221;, ggsimutkin@gmail.com3Mental Health Research Institute of the Federal State Budget Scientific Institution \\&#8221;Tomsk National Research Medical Center of the Russian Academy of Sciences\\&#8221;, bna909@gmail.com4Mental Health Research Institute of the Federal State Budget Scientific Institution \\&#8221;Tomsk National Research Medical Center of the Russian Academy of Sciences\\&#8221;, ivanovaniipz@gmail.com The investigation the relationship between BDNF, NGF and NRG1 genotypes with remission in patients with MDD was made in a group of 208 patients. The study showed that rs3924999 of the NRG1 gene was associated with clinical remission, rated on the HDRS-17 scale on day 28 of antidepressant therapy.<\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2182],"tags":[1815,1814,1228,1816,1817,1818],"_links":{"self":[{"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/posts\/10187"}],"collection":[{"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/comments?post=10187"}],"version-history":[{"count":0,"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/posts\/10187\/revisions"}],"wp:attachment":[{"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/media?parent=10187"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/categories?post=10187"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2020\/wp-json\/wp\/v2\/tags?post=10187"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}