{"id":15910,"date":"2022-06-29T11:32:09","date_gmt":"2022-06-29T04:32:09","guid":{"rendered":"https:\/\/bgrssb.icgbio.ru\/2022\/?p=15910"},"modified":"2022-09-20T10:32:15","modified_gmt":"2022-09-20T03:32:15","slug":"effects-of-chronic-social-stress-on-the-expression-of-carcinogenesis-associated-and-apoptosis-associated-genes-in-the-hypothalamus-of-mice","status":"publish","type":"post","link":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/2022\/06\/29\/effects-of-chronic-social-stress-on-the-expression-of-carcinogenesis-associated-and-apoptosis-associated-genes-in-the-hypothalamus-of-mice\/","title":{"rendered":"Effects of chronic social stress on the expression of carcinogenesis-associated and apoptosis-associated genes in the hypothalamus of mice"},"content":{"rendered":"<p><em>by Kovalenko I.L. | Galyamina A.G. | Smagin D.A. | Kudryavtseva N.N. | Institute of Cytology and<\/em><br \/>\n<em>Genetics, SB RAS, Novosibirsk, Russia\u00a0<\/em><\/p>\n<p><strong>Motivation and Aim<\/strong>: Chronic social stress leads to a mixed anxiety\/depression disorder that<br \/>\nis accompanied by psychogenic immunodeficiency and\u2014as shown previously\u2014by the<br \/>\nstimulation of oncogenic processes in mice. Undoubtedly, the hypothalamus is involved in<br \/>\nthe pathophysiology of psychoemotional disorders and the related immune pathologies and<br \/>\ncancers. In this brain region of male mice with severe depressive symptoms, we aimed to<br \/>\nidentify differentially expressed genes (DEGs) encoding proteins related to mechanisms of<br \/>\ncarcinogenesis and apoptosis.<br \/>\n<strong>Acknowledgements<\/strong>: The study is supported by the Russian Science Foundation (grant \u2116<br \/>\n19-15-00026) and by Budget Project \u2116 FWNR-2022-0019.<\/p>\n<a href=\"https:\/\/bgrssb.icgbio.ru\/2022\/wp-content\/uploads\/sites\/3\/2022\/06\/\u041f\u0440\u0435\u0437\u0435\u043d\u0442\u0430\u0446\u0438\u044f\u041a\u043e\u0432\u0430\u043b\u0435\u043d\u043a\u043e.pdf\" class=\"pdfemb-viewer\" style=\"\" data-width=\"max\" data-height=\"max\"  data-toolbar=\"bottom\" data-toolbar-fixed=\"off\">\u041f\u0440\u0435\u0437\u0435\u043d\u0442\u0430\u0446\u0438\u044f\u041a\u043e\u0432\u0430\u043b\u0435\u043d\u043a\u043e<br\/><\/a>\n","protected":false},"excerpt":{"rendered":"<p>by Kovalenko I.L. | Galyamina A.G. | Smagin D.A. | Kudryavtseva N.N. | Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia\u00a0 Motivation and Aim: Chronic social stress leads to a mixed anxiety\/depression disorder that is accompanied by psychogenic immunodeficiency and\u2014as shown previously\u2014by the stimulation of oncogenic processes in mice. Undoubtedly, the hypothalamus is involved [&hellip;]<\/p>\n","protected":false},"author":3967,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[11],"tags":[269,270,271,272,273],"_links":{"self":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/posts\/15910"}],"collection":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/users\/3967"}],"replies":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/comments?post=15910"}],"version-history":[{"count":1,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/posts\/15910\/revisions"}],"predecessor-version":[{"id":15912,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/posts\/15910\/revisions\/15912"}],"wp:attachment":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/media?parent=15910"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/categories?post=15910"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/tags?post=15910"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}