{"id":16152,"date":"2022-07-05T13:43:14","date_gmt":"2022-07-05T06:43:14","guid":{"rendered":"https:\/\/bgrssb.icgbio.ru\/2022\/?p=16152"},"modified":"2022-09-20T10:31:55","modified_gmt":"2022-09-20T03:31:55","slug":"re-analysis-of-dna-methylationin-genes-associated-with-bronchial-asthma","status":"publish","type":"post","link":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/2022\/07\/05\/re-analysis-of-dna-methylationin-genes-associated-with-bronchial-asthma\/","title":{"rendered":"Re-analysis of DNA methylationin genes associated with bronchial asthma"},"content":{"rendered":"<p><em>by Babushkina Nadezhda | Bragina Elena | Gonchrova Irina | Markov Anton | Kucher Aksana | Babushkina <\/em><em>Nadezhda | Nazarenko Maria | Research Institute of Medical Genetics, Tomsk National Research Medical <\/em><em>Center RAS, Tomsk, Russia\u00a0<\/em><\/p>\n<p>To study the variability of gene methylation patterns, which in our previous studies showed<br \/>\nassociations with bronchial asthma and tuberculosis (which are dystrophic diseases), we re\u0002analyzed two datasets GSE104471 and GSE59339 from the public repository of functional<br \/>\ngenomic data Gene Expression Omnibus (GEO) [1]. The goal of the study was to compare<br \/>\nDNA methylation level associated with bronchial asthma genes in different groups..Type<br \/>\nhere a short description of your report.<br \/>\nThe data obtained as a result of reanalysis on differences in the level of DNA methylation of<br \/>\na number of genes associated with bronchial asthma indicate the potential significance of<br \/>\nepigenetic modifications in predisposition to this pathology<\/p>\n<a href=\"https:\/\/bgrssb.icgbio.ru\/2022\/wp-content\/uploads\/sites\/3\/2022\/07\/BGRS-SB-2022-BA.pdf\" class=\"pdfemb-viewer\" style=\"\" data-width=\"max\" data-height=\"max\"  data-toolbar=\"bottom\" data-toolbar-fixed=\"off\">BGRS-SB-2022-BA<br\/><\/a>\n","protected":false},"excerpt":{"rendered":"<p>by Babushkina Nadezhda | Bragina Elena | Gonchrova Irina | Markov Anton | Kucher Aksana | Babushkina Nadezhda | Nazarenko Maria | Research Institute of Medical Genetics, Tomsk National Research Medical Center RAS, Tomsk, Russia\u00a0 To study the variability of gene methylation patterns, which in our previous studies showed associations with bronchial asthma and tuberculosis [&hellip;]<\/p>\n","protected":false},"author":3967,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[12],"tags":[387,26,388],"_links":{"self":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/posts\/16152"}],"collection":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/users\/3967"}],"replies":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/comments?post=16152"}],"version-history":[{"count":2,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/posts\/16152\/revisions"}],"predecessor-version":[{"id":18084,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/posts\/16152\/revisions\/18084"}],"wp:attachment":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/media?parent=16152"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/categories?post=16152"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/ru\/wp-json\/wp\/v2\/tags?post=16152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}