{"id":13673,"date":"2022-03-11T04:17:44","date_gmt":"2022-03-11T04:17:44","guid":{"rendered":"https:\/\/bgrssb.icgbio.ru\/2022\/?page_id=13673"},"modified":"2022-05-23T16:49:48","modified_gmt":"2022-05-23T09:49:48","slug":"symposium-computational-structural-biology-and-pharmacology","status":"publish","type":"page","link":"https:\/\/bgrssb.icgbio.ru\/2022\/symposium-computational-structural-biology-and-pharmacology\/","title":{"rendered":"Symposium \u201cStructural biology and pharmacology: computational and experimental approaches\u201c"},"content":{"rendered":"

Structural biology and pharmacology: computational and experimental approaches<\/h1>\n

Chairs<\/strong><\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n
Section “From biologically active substances to pharmaceutical products. The role of synchrotron radiation and advanced instrumental techniques”<\/strong><\/span><\/td>\n<\/tr>\n
\"\"<\/td>\nSergey Arkhipov<\/a>, Novosibirsk State University, Novosibirsk; Synchrotron Radiation Facility SKIF, Koltsovo, Russia<\/td>\n<\/tr>\n
\"\"<\/td>\nYan Zubavichus<\/a>, Boreskov Institute of Catalysis of SB RAS, Novosibirsk; Synchrotron Radiation Facility SKIF, Koltsovo<\/td>\n<\/tr>\n
\"\"<\/td>\nElena Boldyreva<\/a>, Boreskov Institute of Catalysis of SB RAS; Novosibirsk State University, Novosibirsk, Russia<\/td>\n<\/tr>\n
\"\"<\/td>\nAnastasiya Bakulina<\/a>, Novosibirsk State University, Novosibirsk, Russia<\/td>\n<\/tr>\n
Section “Structural biology of proteins and membranes”<\/strong><\/span><\/td>\n<\/tr>\n
\"\"<\/td>\nRoman Efremov<\/a>, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia<\/td>\n<\/tr>\n
\"\"<\/td>\nYulia Dyakova<\/a><\/p>\n

NRC “Kurchatov Institute”, Moscow, Russia<\/td>\n<\/tr>\n

Section “Chemoinformatics and chemical biology”<\/strong><\/span><\/td>\n<\/tr>\n
<\/a><\/td>\nVladimir Poroikov<\/a>, Institute of Biomedical Chemistry, Moscow, Russia<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Annotation<\/strong><\/p>\n

    \n
  • Genomic and postgenomic approaches in drug discovery\u00a0Disease interactome<\/li>\n
  • Repurposing of the existing drugs<\/li>\n
  • Pathway analysis and personalized medicine<\/li>\n
  • Molecular modeling in drug design & discovery<\/li>\n
  • Chemoinformatics and chemical biology<\/li>\n<\/ul>\n

     <\/p>\n

    The section “Structural Biology of Proteins and Membranes<\/strong>” brings together the works of leading Russian and international teams devoted to the atomistic study of the structural organization and dynamic behavior of cell membranes. In this case, membrane\/membrane-active proteins and peptides, lipid bilayer molecules, as well as their complexes are considered. Special attention is paid to the analysis of the most complex networks of molecular interactions between all components of these mesoscopic systems. A rich arsenal of modern experimental and computational methods is presented, including: X-ray, cryo-EM, NMR spectroscopy, small-angle X-ray scattering, electrochemical measurements, neutron scattering, molecular dynamics, structural bioinformatics, etc. The research results reveal new interesting relationships between the structure and dynamics of biological membranes and their functioning, allow deciphering the molecular mechanisms of a number of vital processes in the cell. These data form the fundamental basis for the rational design of new classes of drugs and therapies to combat socially significant diseases.<\/p>\n","protected":false},"excerpt":{"rendered":"

    Structural biology and pharmacology: computational and experimental approaches Chairs Section “From biologically active substances to pharmaceutical products. The role of synchrotron radiation and advanced instrumental techniques” Sergey Arkhipov, Novosibirsk State University, Novosibirsk; Synchrotron Radiation Facility SKIF, Koltsovo, Russia Yan Zubavichus, Boreskov Institute of Catalysis of SB RAS, Novosibirsk; Synchrotron Radiation Facility SKIF, Koltsovo Elena Boldyreva, […]<\/p>\n","protected":false},"author":148,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/pages\/13673"}],"collection":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/users\/148"}],"replies":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/comments?post=13673"}],"version-history":[{"count":22,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/pages\/13673\/revisions"}],"predecessor-version":[{"id":14699,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/pages\/13673\/revisions\/14699"}],"wp:attachment":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/media?parent=13673"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}