{"id":15946,"date":"2022-06-30T15:10:16","date_gmt":"2022-06-30T08:10:16","guid":{"rendered":"https:\/\/bgrssb.icgbio.ru\/2022\/?p=15946"},"modified":"2022-09-20T10:32:15","modified_gmt":"2022-09-20T03:32:15","slug":"domestication-explains-2-3-of-differential-gene-expression-variance-between-domestic-and-wild-animals-the-remaining-1-3-reflects-intraspecific-and-interspecific-variation","status":"publish","type":"post","link":"https:\/\/bgrssb.icgbio.ru\/2022\/2022\/06\/30\/domestication-explains-2-3-of-differential-gene-expression-variance-between-domestic-and-wild-animals-the-remaining-1-3-reflects-intraspecific-and-interspecific-variation\/","title":{"rendered":"Domestication explains 2\/3 of differential gene expression variance between domestic and wild animals; the remaining 1\/3 reflects intraspecific and interspecific variation"},"content":{"rendered":"<p><em>by Chadaeva Irina | Ponomarenko P. | Kozhemyakina R. | Suslov V. | Bogomolov A. | Klimova<br \/>\nN. | Shikhevich S. | Savinkova L. | Oshchepkov D. | Kolchanov N.A. | Markel<br \/>\nA. | Ponomarenko M. | ICG SB RAS<\/em><\/p>\n<p>Here we sequenced hypothalamic transcriptomes of tame and aggressive rats,<br \/>\nidentified their differentially expressed genes (DEGs), and applied principal<br \/>\ncomponent analysis to compare them with all the known DEGs of domestic versus<br \/>\nwild animals that we could find. Two principal components, PC1 and PC2,<br \/>\nrespectively explained 67% and 33% of DEGs variance between domestic and wild<br \/>\nanimals.<br \/>\nOn a laboratory model of the animal domestication, tame and aggressive rats, the<br \/>\nrelationship of differential gene expression with two factors was shown &#8211; with<br \/>\nartificial selection (domestication) and intraspecific variability<br \/>\nTwo processes were quantified, domestication and microevolution at the same scale<br \/>\n(genome-wide analysis)<br \/>\nThey respectively explain 2\/3 and 1\/3 of the differences in differential gene<br \/>\nexpression in domestic and wild animals as a response of genomes to the impact of<br \/>\nartificial and natural habitat factors<\/p>\n<a href=\"https:\/\/bgrssb.icgbio.ru\/2022\/wp-content\/uploads\/sites\/3\/2022\/06\/Chadaeva_BGRS_2022.pdf\" class=\"pdfemb-viewer\" style=\"\" data-width=\"max\" data-height=\"max\"  data-toolbar=\"bottom\" data-toolbar-fixed=\"off\">Chadaeva_BGRS_2022<br\/><\/a>\n","protected":false},"excerpt":{"rendered":"<p>by Chadaeva Irina | Ponomarenko P. | Kozhemyakina R. | Suslov V. | Bogomolov A. | Klimova N. | Shikhevich S. | Savinkova L. | Oshchepkov D. | Kolchanov N.A. | Markel A. | Ponomarenko M. | ICG SB RAS Here we sequenced hypothalamic transcriptomes of tame and aggressive rats, identified their differentially expressed genes [&hellip;]<\/p>\n","protected":false},"author":3967,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[11],"tags":[296,294,299,298,297,295,293,67],"_links":{"self":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/posts\/15946"}],"collection":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/users\/3967"}],"replies":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/comments?post=15946"}],"version-history":[{"count":1,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/posts\/15946\/revisions"}],"predecessor-version":[{"id":15948,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/posts\/15946\/revisions\/15948"}],"wp:attachment":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/media?parent=15946"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/categories?post=15946"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/tags?post=15946"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}