{"id":16071,"date":"2022-07-04T22:22:29","date_gmt":"2022-07-04T15:22:29","guid":{"rendered":"https:\/\/bgrssb.icgbio.ru\/2022\/?p=16071"},"modified":"2022-09-20T10:31:55","modified_gmt":"2022-09-20T03:31:55","slug":"exploring-lncrna-mrna-signatures-in-relapsed-acute-myeloid-leukemia-compared-with-primary-tumors","status":"publish","type":"post","link":"https:\/\/bgrssb.icgbio.ru\/2022\/2022\/07\/04\/exploring-lncrna-mrna-signatures-in-relapsed-acute-myeloid-leukemia-compared-with-primary-tumors\/","title":{"rendered":"Exploring lncRNA-mRNA signatures in relapsed acute myeloid leukemia compared with primary tumors"},"content":{"rendered":"<p><em>by Elizaveta Kulaeva | Academy of Biology and Biotechnology, Southern Federal University, Rostov-onDon, Russia<\/em><\/p>\n<p>Long non-coding RNAs (lncRNAs) play a role in the pathogenesis<br \/>\nof acute myeloid leukemia (AML) by affecting gene expression, including in pediatric<br \/>\nAML. Deregulation of lncRNAs patterns has the potential to regulate tumor drug<br \/>\nresistance and sustaining of leukemic stem cells. Here we investigated the expression<br \/>\npatterns of lncRNAs and mRNAs in relapsed tumors compared to primary tumors, using<br \/>\nTARGET-AML project data<\/p>\n<a href=\"https:\/\/bgrssb.icgbio.ru\/2022\/wp-content\/uploads\/sites\/3\/2022\/07\/Untitled-7.pdf\" class=\"pdfemb-viewer\" style=\"\" data-width=\"max\" data-height=\"max\"  data-toolbar=\"bottom\" data-toolbar-fixed=\"off\">Untitled (7)<br\/><\/a>\n","protected":false},"excerpt":{"rendered":"<p>by Elizaveta Kulaeva | Academy of Biology and Biotechnology, Southern Federal University, Rostov-onDon, Russia Long non-coding RNAs (lncRNAs) play a role in the pathogenesis of acute myeloid leukemia (AML) by affecting gene expression, including in pediatric AML. Deregulation of lncRNAs patterns has the potential to regulate tumor drug resistance and sustaining of leukemic stem cells. [&hellip;]<\/p>\n","protected":false},"author":3967,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[12],"tags":[365,366,364],"_links":{"self":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/posts\/16071"}],"collection":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/users\/3967"}],"replies":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/comments?post=16071"}],"version-history":[{"count":1,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/posts\/16071\/revisions"}],"predecessor-version":[{"id":16073,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/posts\/16071\/revisions\/16073"}],"wp:attachment":[{"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/media?parent=16071"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/categories?post=16071"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2022\/wp-json\/wp\/v2\/tags?post=16071"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}