{"id":719,"date":"2026-02-16T12:38:11","date_gmt":"2026-02-16T09:38:11","guid":{"rendered":"https:\/\/bgrssb.icgbio.ru\/2026\/?page_id=719"},"modified":"2026-02-20T13:51:48","modified_gmt":"2026-02-20T10:51:48","slug":"section_3_2","status":"publish","type":"page","link":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/section_3_2\/","title":{"rendered":"Section \u201cPharmacology, chemoinformatics and chemical biology\u201d"},"content":{"rendered":"<p data-start=\"0\" data-end=\"153\"><span style=\"font-family: arial, helvetica, sans-serif; font-size: 10pt;\">Section \u201cPharmacology, Chemoinformatics, and Chemical Biology\u201d focuses on the discovery and development of pharmaceuticals using <em data-start=\"133\" data-end=\"144\">in silico<\/em> methods.<\/span><\/p>\n<p><span style=\"font-family: arial, helvetica, sans-serif; font-size: 10pt;\">Main areas of the section:<\/span><\/p>\n<ul data-start=\"182\" data-end=\"1059\" data-is-last-node=\"\" data-is-only-node=\"\">\n<li data-start=\"182\" data-end=\"279\"><span style=\"font-family: arial, helvetica, sans-serif; font-size: 10pt;\">omics data and network pharmacology for identifying potential biomarkers and molecular targets;<\/span><\/li>\n<li data-start=\"182\" data-end=\"279\"><span style=\"font-family: arial, helvetica, sans-serif; font-size: 10pt;\">discovery and optimization of pharmacological compounds using structure-based molecular modeling of the target macromolecule;<\/span><\/li>\n<li data-start=\"408\" data-end=\"544\"><span style=\"font-family: arial, helvetica, sans-serif; font-size: 10pt;\">discovery and optimization of pharmacological compounds using machine learning and artificial intelligence based on ligand structures;<\/span><\/li>\n<li data-start=\"545\" data-end=\"663\"><span style=\"font-family: arial, helvetica, sans-serif; font-size: 10pt;\">computer-aided screening and design of multi-target pharmacological compounds with pleiotropic mechanisms of action;<\/span><\/li>\n<li data-start=\"664\" data-end=\"726\"><span style=\"font-family: arial, helvetica, sans-serif; font-size: 10pt;\">drug repurposing based on <em data-start=\"692\" data-end=\"703\">in silico<\/em> hypothesis generation;<\/span><\/li>\n<li data-start=\"727\" data-end=\"805\"><span style=\"font-family: arial, helvetica, sans-serif; font-size: 10pt;\">computational toxicology and safety assessment of potential drug candidates;<\/span><\/li>\n<li data-start=\"806\" data-end=\"904\"><span style=\"font-family: arial, helvetica, sans-serif; font-size: 10pt;\">use of digital twins to reduce the scope of experimental studies in pharmacology and toxicology;<\/span><\/li>\n<li data-start=\"905\" data-end=\"979\"><span style=\"font-family: arial, helvetica, sans-serif; font-size: 10pt;\">development of <em data-start=\"922\" data-end=\"933\">in silico<\/em> models: information sources and data quality;<\/span><\/li>\n<li data-start=\"980\" data-end=\"1059\" data-is-last-node=\"\"><span style=\"font-family: arial, helvetica, sans-serif; font-size: 10pt;\">regulatory and ethical aspects of applying computational drug design methods.<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Section \u201cPharmacology, Chemoinformatics, and Chemical Biology\u201d focuses on the discovery and development of pharmaceuticals using in silico methods. Main areas of the section: omics data and network pharmacology for identifying potential biomarkers and molecular targets; discovery and optimization of pharmacological compounds using structure-based molecular modeling of the target macromolecule; discovery and optimization of pharmacological compounds [&hellip;]<\/p>\n","protected":false},"author":3967,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/pages\/719"}],"collection":[{"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/users\/3967"}],"replies":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/comments?post=719"}],"version-history":[{"count":3,"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/pages\/719\/revisions"}],"predecessor-version":[{"id":836,"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/pages\/719\/revisions\/836"}],"wp:attachment":[{"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/media?parent=719"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}