The interstitial space, as a critical component of connective tissue, has a complex architecture and is distributed throughout all tissues and organs of humans and animals. Interest in the interstitium has been rapidly increasing in recent years, as it is regarded as the largest organ, ensuring the movement of fluids, biopolymers, crystalloids, and cells within the body.<\/p>\n
Interstitial fluid can travel considerable distances along extravascular pathways (interstitial channels) between fibrous matrices and connective-tissue cells.<\/p>\n
Interstitial channels may act as conduits for electromagnetic signals of varying frequency and intensity (including lasers, LEDs, and broadband light in the visible and infrared ranges), and also serve as a carrier medium for metabolic substrates, waste products, and immune mediators.<\/p>\n
Although the interstitium is not formally part of the lymphatic system, it represents an important link in tissue-fluid circulation and the initial stage of lymphatic drainage. The structure and composition of the interstitium in different organs and tissues share common features while also exhibiting distinct differences.<\/p>\n
As an autonomous formation, interstitial fluid has the ability to form liquid-crystalline structures under the influence of the geometry of the occupied or displaced volume, external electromagnetic fields (including coherent fields), heat fluxes, and ionizing radiation.<\/p>\n
Orientational ordering leads to considering the liquid-crystalline medium as soft or structured matter. This, in turn, results in a substantial increase in the complexity of its mechanics and electrodynamics and gives rise to many properties that have no analogues in conventional substances.<\/p>\n
These characteristics of the interstitial space are important both for shaping modern concepts of new fundamental aspects of the structure and functioning of human and animal organisms, and for addressing a wide range of problems in contemporary medicine and pharmacology.<\/p>\n The interstitial space, as a critical component of connective tissue, has a complex architecture and is distributed throughout all tissues and organs of humans and animals. Interest in the interstitium has been rapidly increasing in recent years, as it is regarded as the largest organ, ensuring the movement of fluids, biopolymers, crystalloids, and cells within […]<\/p>\n","protected":false},"author":3967,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/pages\/824"}],"collection":[{"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/users\/3967"}],"replies":[{"embeddable":true,"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/comments?post=824"}],"version-history":[{"count":10,"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/pages\/824\/revisions"}],"predecessor-version":[{"id":842,"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/pages\/824\/revisions\/842"}],"wp:attachment":[{"href":"https:\/\/bgrssb.icgbio.ru\/2026\/en\/wp-json\/wp\/v2\/media?parent=824"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Keywords<\/span><\/span><\/summary>\n
\n\n
\n \nEnglish<\/th>\n \u0420\u0443\u0441\u0441\u043a\u0438\u0439<\/th>\n<\/tr>\n<\/thead>\n \n Interstitial space and extravascular drainage\/transport pathways<\/td>\n \u0418\u043d\u0442\u0435\u0440\u0441\u0442\u0438\u0446\u0438\u0430\u043b\u044c\u043d\u043e\u0435 \u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0441\u0442\u0432\u043e \u0438 \u0432\u043d\u0435\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u044b\u0435 \u0434\u0440\u0435\u043d\u0430\u0436\u043d\u043e-\u0442\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u043d\u044b\u0435 \u043f\u0443\u0442\u0438<\/td>\n<\/tr>\n \n Unrecognized Interstitium<\/td>\n \u041d\u0435\u0440\u0430\u0441\u043f\u043e\u0437\u043d\u0430\u0432\u0430\u0435\u043c\u044b\u0439 \u0418\u043d\u0442\u0435\u0440\u0441\u0442\u0438\u0446\u0438\u0439<\/td>\n<\/tr>\n \n Fibrous matrices<\/td>\n \u0412\u043e\u043b\u043e\u043a\u043d\u0438\u0441\u0442\u044b\u0435 \u043c\u0430\u0442\u0440\u0438\u0446\u044b<\/td>\n<\/tr>\n \n Interfacial zone<\/td>\n \u041c\u0435\u0436\u0444\u0430\u0437\u043d\u0430\u044f \u0437\u043e\u043d\u0430<\/td>\n<\/tr>\n \n The meshwork of fibrous connective tissues<\/td>\n \u0412\u043e\u043b\u043e\u043a\u043d\u0438\u0441\u0442\u0430\u044f \u0441\u0435\u0442\u043a\u0430 \u0441\u043e\u0435\u0434\u0438\u043d\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0442\u043a\u0430\u043d\u043d\u044b\u0445 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440<\/td>\n<\/tr>\n \n Connective tissue space<\/td>\n \u0421\u043e\u0435\u0434\u0438\u043d\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0442\u043a\u0430\u043d\u043d\u043e\u0435 \u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0441\u0442\u0432\u043e<\/td>\n<\/tr>\n \n Connective tissue channels<\/td>\n \u0421\u043e\u0435\u0434\u0438\u043d\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0442\u043a\u0430\u043d\u043d\u044b\u0435 \u043a\u0430\u043d\u0430\u043b\u044b<\/td>\n<\/tr>\n \n Tissue architecture: collagen organization<\/td>\n \u0422\u043a\u0430\u043d\u0435\u0432\u0430\u044f \u0430\u0440\u0445\u0438\u0442\u0435\u043a\u0442\u0443\u0440\u0430: \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u0430\u0446\u0438\u044f \u043a\u043e\u043b\u043b\u0430\u0433\u0435\u043d\u0430<\/td>\n<\/tr>\n \n Structural framework of fibrous connective tissues<\/td>\n \u0421\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u043d\u044b\u0439 \u043a\u0430\u0440\u043a\u0430\u0441 \u0432\u043e\u043b\u043e\u043a\u043d\u0438\u0441\u0442\u043e\u0439 \u0441\u043e\u0435\u0434\u0438\u043d\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0439 \u0442\u043a\u0430\u043d\u0438<\/td>\n<\/tr>\n \n \u201cSlit-shaped\u201d vascular adventitia<\/td>\n \u00ab\u0429\u0435\u043b\u0435\u0432\u0438\u0434\u043d\u0430\u044f\u00bb \u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u0430\u044f \u0430\u0434\u0432\u0435\u043d\u0442\u0438\u0446\u0438\u044f<\/td>\n<\/tr>\n \n \u2018Paravascular\u2019 fluid circulation<\/td>\n \u041f\u0430\u0440\u0430\u0432\u0430\u0441\u043a\u0443\u043b\u044f\u0440\u043d\u0430\u044f \u0446\u0438\u0440\u043a\u0443\u043b\u044f\u0446\u0438\u044f \u0436\u0438\u0434\u043a\u043e\u0441\u0442\u0438<\/td>\n<\/tr>\n \n A long-distance fluid transport pathway<\/td>\n \u041f\u0443\u0442\u0438 \u0442\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u0438\u0440\u043e\u0432\u043a\u0438 \u0436\u0438\u0434\u043a\u043e\u0441\u0442\u0438 \u043d\u0430 \u0431\u043e\u043b\u044c\u0448\u0438\u0435 \u0440\u0430\u0441\u0441\u0442\u043e\u044f\u043d\u0438\u044f<\/td>\n<\/tr>\n \n PACT (PACT pathway)<\/td>\n \u041f\u0435\u0440\u0438\u0432\u0430\u0441\u043a\u0443\u043b\u044f\u0440\u043d\u044b\u0435 \u0430\u0434\u0432\u0435\u043d\u0442\u0438\u0446\u0438\u0430\u043b\u044c\u043d\u044b\u0435 \u0441\u043e\u0435\u0434\u0438\u043d\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0442\u043a\u0430\u043d\u043d\u044b\u0435 \u043f\u0443\u0442\u0438<\/td>\n<\/tr>\n \n Longitudinal transport channel in a PACT pathway<\/td>\n \u041f\u0440\u043e\u0434\u043e\u043b\u044c\u043d\u044b\u0439 \u0442\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u043d\u044b\u0439 \u043a\u0430\u043d\u0430\u043b \u0432 PACT<\/td>\n<\/tr>\n \n Extravascular fluid transport system<\/td>\n \u0412\u043d\u0435\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u0430\u044f \u0441\u0438\u0441\u0442\u0435\u043c\u0430 \u0442\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u0430 \u0436\u0438\u0434\u043a\u043e\u0441\u0442\u0438<\/td>\n<\/tr>\n \n ITZ – interconnected topologically interfacial zones<\/td>\n ITZ – \u0432\u0437\u0430\u0438\u043c\u043e\u0441\u0432\u044f\u0437\u0430\u043d\u043d\u044b\u0435 \u0442\u043e\u043f\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438 \u043c\u0435\u0436\u0444\u0430\u0437\u043d\u044b\u0435 \u0437\u043e\u043d\u044b<\/td>\n<\/tr>\n \n Active interfacial dynamic transport of fluid in a network of fibrous connective tissues throughout the whole body<\/td>\n \u0410\u043a\u0442\u0438\u0432\u043d\u044b\u0439 \u043c\u0435\u0436\u0444\u0430\u0437\u043d\u044b\u0439 \u0434\u0438\u043d\u0430\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0442\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442 \u0436\u0438\u0434\u043a\u043e\u0441\u0442\u0438 \u0432 \u0441\u0435\u0442\u0438 \u0432\u043e\u043b\u043e\u043a\u043d\u0438\u0441\u0442\u044b\u0445 \u0441\u043e\u0435\u0434\u0438\u043d\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0442\u043a\u0430\u043d\u0435\u0439 \u043f\u043e \u0432\u0441\u0435\u043c\u0443 \u0442\u0435\u043b\u0443<\/td>\n<\/tr>\n \n Low hydraulic resistance channel<\/td>\n \u041a\u0430\u043d\u0430\u043b \u0441 \u043d\u0438\u0437\u043a\u0438\u043c \u0433\u0438\u0434\u0440\u0430\u0432\u043b\u0438\u0447\u0435\u0441\u043a\u0438\u043c \u0441\u043e\u043f\u0440\u043e\u0442\u0438\u0432\u043b\u0435\u043d\u0438\u0435\u043c<\/td>\n<\/tr>\n \n A biotic interfacial fluid transport phenomenon<\/td>\n \u0424\u0435\u043d\u043e\u043c\u0435\u043d \u0431\u0438\u043e\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u043c\u0435\u0436\u0444\u0430\u0437\u043d\u043e\u0433\u043e \u0442\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u0430 \u0436\u0438\u0434\u043a\u043e\u0441\u0442\u0438<\/td>\n<\/tr>\n \n Nanoconfined diffusive mass transport regimes<\/td>\n \u041d\u0430\u043d\u043e\u043e\u0433\u0440\u0430\u043d\u0438\u0447\u0435\u043d\u043d\u044b\u0435 \u0434\u0438\u0444\u0444\u0443\u0437\u0438\u043e\u043d\u043d\u044b\u0435 \u0440\u0435\u0436\u0438\u043c\u044b \u043c\u0430\u0441\u0441\u043e\u043f\u0435\u0440\u0435\u043d\u043e\u0441\u0430<\/td>\n<\/tr>\n \n Nanoscale fluid transport<\/td>\n \u041d\u0430\u043d\u043e\u0440\u0430\u0437\u043c\u0435\u0440\u043d\u044b\u0439 \u0442\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442 \u0436\u0438\u0434\u043a\u043e\u0441\u0442\u0438<\/td>\n<\/tr>\n \n Modeling of human interstitial fluid<\/td>\n \u041c\u043e\u0434\u0435\u043b\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435 \u0438\u043d\u0442\u0435\u0440\u0441\u0442\u0438\u0446\u0438\u0430\u043b\u044c\u043d\u043e\u0439 \u0436\u0438\u0434\u043a\u043e\u0441\u0442\u0438 \u0447\u0435\u043b\u043e\u0432\u0435\u043a\u0430<\/td>\n<\/tr>\n \n Biophysical origin of diseases<\/td>\n \u0411\u0438\u043e\u0444\u0438\u0437\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u043f\u0440\u043e\u0438\u0441\u0445\u043e\u0436\u0434\u0435\u043d\u0438\u0435 \u0431\u043e\u043b\u0435\u0437\u043d\u0435\u0439<\/td>\n<\/tr>\n \n Photobiomodulation, photomedicine, application of photobiomodulation therapy<\/td>\n \u0424\u043e\u0442\u043e\u0431\u0438\u043e\u043c\u043e\u0434\u0443\u043b\u044f\u0446\u0438\u044f, \u0444\u043e\u0442\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430, \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0435 \u0444\u043e\u0442\u043e\u0431\u0438\u043e\u043c\u043e\u0434\u0443\u043b\u044f\u0446\u0438\u043e\u043d\u043d\u043e\u0439 \u0442\u0435\u0440\u0430\u043f\u0438\u0438<\/td>\n<\/tr>\n \n Optics and biophotonics of human skin<\/td>\n \u041e\u043f\u0442\u0438\u043a\u0430 \u0438 \u0431\u0438\u043e\u0444\u043e\u0442\u043e\u043d\u0438\u043a\u0430 \u043a\u043e\u0436\u0438 \u0447\u0435\u043b\u043e\u0432\u0435\u043a\u0430<\/td>\n<\/tr>\n \n A structure of human water, biological water dynamics<\/td>\n \u0421\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u0430 \u0447\u0435\u043b\u043e\u0432\u0435\u0447\u0435\u0441\u043a\u043e\u0439 \u0432\u043e\u0434\u044b, \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0434\u0438\u043d\u0430\u043c\u0438\u043a\u0430 \u0432\u043e\u0434\u044b<\/td>\n<\/tr>\n \n Acupuncture meridian system in traditional chinese medicine<\/td>\n \u0421\u0438\u0441\u0442\u0435\u043c\u0430 \u0430\u043a\u0443\u043f\u0443\u043d\u043a\u0442\u0443\u0440\u043d\u044b\u0445 \u043c\u0435\u0440\u0438\u0434\u0438\u0430\u043d\u043e\u0432 \u0432 \u0442\u0440\u0430\u0434\u0438\u0446\u0438\u043e\u043d\u043d\u043e\u0439 \u043a\u0438\u0442\u0430\u0439\u0441\u043a\u043e\u0439 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0435<\/td>\n<\/tr>\n \n Infrared thermography, terahertz tissue spectroscopy in diagnosis<\/td>\n \u0418\u043d\u0444\u0440\u0430\u043a\u0440\u0430\u0441\u043d\u0430\u044f \u0442\u0435\u0440\u043c\u043e\u0433\u0440\u0430\u0444\u0438\u044f, \u0442\u0435\u0440\u0430\u0433\u0435\u0440\u0446\u043e\u0432\u0430\u044f \u0441\u043f\u0435\u043a\u0442\u0440\u043e\u0441\u043a\u043e\u043f\u0438\u044f \u0442\u043a\u0430\u043d\u0435\u0439 \u0432 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0435<\/td>\n<\/tr>\n \n Thermal imager as a diagnostic device<\/td>\n \u0422\u0435\u043f\u043b\u043e\u0432\u0438\u0437\u043e\u0440 \u043a\u0430\u043a \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u043f\u0440\u0438\u0431\u043e\u0440.<\/td>\n<\/tr>\n \n Modeling of light transport in human tissues<\/td>\n \u041c\u043e\u0434\u0435\u043b\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435 \u0442\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u0430 \u0441\u0432\u0435\u0442\u043e\u0432\u043e\u0433\u043e \u043f\u043e\u0442\u043e\u043a\u0430 \u0432 \u0442\u043a\u0430\u043d\u044f\u0445 \u0447\u0435\u043b\u043e\u0432\u0435\u043a\u0430<\/td>\n<\/tr>\n \n Zakharyin-Ged zones, human organs, ways of transmitting information.<\/td>\n \u0417\u043e\u043d\u044b \u0417\u0430\u0445\u0430\u0440\u044c\u0438\u043d\u0430 \u2013 \u0413\u0435\u0434\u0430, \u043e\u0440\u0433\u0430\u043d\u044b \u0447\u0435\u043b\u043e\u0432\u0435\u043a\u0430, \u043f\u0443\u0442\u0438 \u043f\u0435\u0440\u0435\u0434\u0430\u0447\u0438 \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u0438.<\/td>\n<\/tr>\n \n Human information field.<\/td>\n \u0418\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u043e\u043d\u043d\u043e\u0435 \u043f\u043e\u043b\u0435 \u0447\u0435\u043b\u043e\u0432\u0435\u043a\u0430.<\/td>\n<\/tr>\n \n Light therapy, spectra, laser, wavelength.<\/td>\n \u0421\u0432\u0435\u0442\u043e\u043b\u0435\u0447\u0435\u043d\u0438\u0435, \u0441\u043f\u0435\u043a\u0442\u0440\u044b, \u043b\u0430\u0437\u0435\u0440, \u0434\u043b\u0438\u043d\u0430 \u0432\u043e\u043b\u043d\u044b.<\/td>\n<\/tr>\n \n Methods of influencing acupuncture points.<\/td>\n \u041c\u0435\u0442\u043e\u0434\u044b \u0432\u043e\u0437\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f \u043d\u0430 \u0430\u043a\u0443\u043f\u0443\u043d\u043a\u0442\u0443\u0440\u043d\u044b\u0435 \u0442\u043e\u0447\u043a\u0438.<\/td>\n<\/tr>\n \n Terahertz radiation affects living tissue.<\/td>\n \u0422\u0435\u0440\u0430\u0433\u0435\u0440\u0446\u043e\u0432\u043e\u0435 \u0438\u0437\u043b\u0443\u0447\u0435\u043d\u0438\u0435 \u2013 \u0432\u043e\u0437\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435 \u043d\u0430 \u0436\u0438\u0432\u044b\u0435 \u0442\u043a\u0430\u043d\u0438.<\/td>\n<\/tr>\n \n High intensity laser therapy.<\/td>\n \u0412\u044b\u0441\u043e\u043a\u043e\u0438\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u0430\u044f \u043b\u0430\u0437\u0435\u0440\u043d\u0430\u044f \u0442\u0435\u0440\u0430\u043f\u0438\u044f.<\/td>\n<\/tr>\n \n Water, liquid crystal, water cluster structure,<\/td>\n \u0412\u043e\u0434\u0430, \u0436\u0438\u0434\u043a\u0438\u0439 \u043a\u0440\u0438\u0441\u0442\u0430\u043b\u043b, \u043a\u043b\u0430\u0441\u0442\u0435\u0440\u043d\u0430\u044f \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u0430 \u0432\u043e\u0434\u044b,<\/td>\n<\/tr>\n \n Crystal structure of liquids in the human body.<\/td>\n \u041a\u0440\u0438\u0441\u0442\u0430\u043b\u043b\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u0430 \u0436\u0438\u0434\u043a\u043e\u0441\u0442\u0435\u0439 \u0432 \u0442\u0435\u043b\u0435 \u0447\u0435\u043b\u043e\u0432\u0435\u043a\u0430.<\/td>\n<\/tr>\n \n Interstitial fluid is a liquid crystal.<\/td>\n \u0418\u043d\u0442\u0435\u0440\u0441\u0442\u0438\u0446\u0438\u0430\u043b\u044c\u043d\u0430\u044f \u0436\u0438\u0434\u043a\u043e\u0441\u0442\u044c \u2013 \u0436\u0438\u0434\u043a\u0438\u0439 \u043a\u0440\u0438\u0441\u0442\u0430\u043b\u043b.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/details>\n","protected":false},"excerpt":{"rendered":"