Poster (download)
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Irina Kim1, Alexander Lykov2, Lubov Rachkovskaya3, Maria Surovtseva4, Edmund Rachkovsky5, Olga Poveshchenko6
1Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics SB RAS Novosibirsk, Russia, kii5@yandex.ru
2Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics SB RAS Novosibirsk, Russia, aplykov2@mail.ru
3Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics SB RAS Novosibirsk, Russia, noolit@niikel.ru
4Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics SB RAS Novosibirsk, Russia, mfelde@ngs.ru
5Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics SB RAS Novosibirsk, Russia, reed@academ.org
6Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics SB RAS Novosibirsk, Russia , Meshalkin National Medical Research Center, Ministry of Health of Russian Federation Novosibirsk, Russia, poveschenkoov@yandex.ru
In this study, Оі-aluminum-silica-single-wall carbon nanotubes carriers were synthesized and confirmed by scanning electron microscope, emission spectrometry, spectrophotometry. In the in vitro assays, the cytotoxicity on human bone marrow mesenchymal stem cells, and endothelial cell line EA.hy 926 were investigated by MTT assay, Griess reagent, and mixture of benzidine and hydrogen peroxide. The results of the proliferation, nitrogen production and intracellular myeloperoxidase activity showed that the Оі-aluminum-silica-single-wall carbon nanotubes carriers did not have a pronounced toxic effect on human cells. In conclusion, our results confirm that composition of Оі-aluminum-silica-single-wall carbon nanotubes may be used as carriers.