International Multiconference “Bioinformatics of Genome Regulation and Structure\Systems Biology”

Tag

adaptation

3 RESULTS
Systems Biology of Aging sectionWay to longevity: role of antioxidant defense gene polymorphisms in successful adaptation

Way to longevity: role of antioxidant defense gene polymorphisms in successful adaptation

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Poster (download)

[pdf-embedder url=”https://bgrssb.icgbio.ru/wp-content/uploads/2020/07/156.pdf”]
Vera Erdman1, Timur Nasibullin2, Ilsia Tuktarova3, Ksenia Danilko4, Alisa Matua5, Tatiana Viktorova6, Olga Mustafina7
1IBG UFRC RAS, danivera@mail.ru
2IBG UFRC RAS, nasibullintr@yandex.ru
3IBG UFRC RAS, iltuk@mail.ru
4BSMU, kse-danilko@yandex.ru
5SRI EPT ASA, azmatua@mail.ru
6BSMU, t_vict@mail.ru
7IBG UFRC RAS, anmareg@mail.ru

We carried out the analysis of associations between polymorphic loci of antioxidant defense genes with ethnicity and longevity. We found the interethnic differences in the distribution of allele frequencies of SOD1, SOD2, CAT, NQO1 genes. For reaching longevity SOD1, SOD2, NQO1, GPX1 genes were significant among Russians, SOD2, РЎРђРў genes – among Tatars, MSRA, РЎРђРў genes – among Bashkirs.

Cognitive Science and Genomics symposiumStudy of personal qualities and EEG activity in a stop signal paradigm in residents of northern regions

Study of personal qualities and EEG activity in a stop signal paradigm in residents of northern regions

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Poster (download)

[pdf-embedder url=”https://bgrssb.icgbio.ru/wp-content/uploads/2020/07/441.pdf”]
Tatiana Asakhova1, Alexander Saprigyn2, Sergey Tamozhnikov3, Alexandra Karpova4, Natalya Borisova5, Elena Afanaseva6, Alexander Savostyanov7
1NSU, Novosibirsk, Russia, t.astakhova@g.nsu.ru
2State Scientific-Research Institute of Physiology & Basic Medicine, Novosibirsk, Russia, saprigyn@mail.ru
3State Scientific-Research Institute of Physiology & Basic Medicine, Novosibirsk, Russia, stam@physiol.ru
4North-Eastern Federal University, Yakutsk, Russia, karpova74@list.ru
5North-Eastern Federal University, Yakutsk, Russia, borinat@yandex.ru
6North-Eastern Federal University, Yakutsk, Russia, eb.afanaseva@mail.ru
7State Scientific-Research Institute of Physiology & Basic Medicine, Novosibirsk, Russia ICG SB RAS, Novosibirsk, Russia NSU, Novosibirsk, Russia, alexander.savostyanov@gmail.com

It is known that the adaptation to new conditions depends on personality traits. The results obtained showed that the lower level of anxiety and neurotism, the better behavioural control and adaptation. Also, the adaptation level is the lowest right after the move to another place, and it grows by the time along with the growth of behavioral control.

Animal Genetics and genomics symposiumGenomic Signals of Adaptation in the Northern Ural and Western Siberian Populations

Genomic Signals of Adaptation in the Northern Ural and Western Siberian Populations

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Poster (download)

[pdf-embedder url=”https://bgrssb.icgbio.ru/wp-content/uploads/2020/07/528.pdf”]
Gennady Khvorykh1, Giang Vu2, Andrey Khrunin3
1Institute of Molecular Genetics of the Russian Academy of Sciences, Moscow, Russia, khvorykh@img.ras.ru
2Moscow Polytechnic University, Moscow, Russia, vuminhgiang135@gmail.com
3Institute of Molecular Genetics of the Russian Academy of Sciences, Moscow, Russia, khrunin@img.ras.ru

The evolution of humans was influenced by environmental conditions, particularly when they left Africa. Exploration of the genetic variations in the populations leaving in extreme climates will lead to better understanding of molecular-genetics mechanisms of adaptation. In the current study we investigated the genome-wide data of Khahty, Mansi, and Nenets people for signatures of selection using the population branch statistic test and revealed strong signals located in a cluster of alcohol dehydrogenase 1 genes. We hypothesize that it can be due to the limited diversity of food intake the indigenous people of the Northern Ural and Siberian experience.