A new method for combining of genetically correlated traits by maximizing of their shared heritability
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Gulnara R. Svishcheva1, Evgeny S. Tiys2, Sofya G. Feoktistova3, Elizaveta E. Elgaeva4, Sodbo Sharapov5, Yakov A. Tsepilov6
1Institute of cytology and genetics, gulsvi@mail.ru
2Institute of cytology and genetics, tiys@bionet.nsc.ru
3Institute of cytology and genetics, sayfutdinovas@gmail.com
4Institute of cytology and genetics, elizabeth.elgaeva@gmail.com
5Institute of cytology and genetics, sharapovsodbo@gmail.com
6Novosibirsk State University, drosophila.simulans@gmail.com
Genetic correlations between phenotypic traits are widely observed phenomena. Many groups of traits have a significant level of shared genetic background. In this work, we suggested a new method for extraction of shared genetic component for genetically correlated phenotypic traits. We applied the method to GWAS results for anthropometric traits.