Accepted_test

InTxSEs:A platform for interactions between bacterial secreted proteins and human proteins

by Yanyan Zhu | Ming Chen | Liya Liu | Yueming Hu | Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou | Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou | Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou | Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou

Abstract ID: 215

Event: BGRS-abstracts

Sections: [Sym 12] Section “Systems theory, big biological data analysis, ontologies and artificial intelligence”

Currently, there is a lack of specialized databases for the interaction between secreted proteins in bacterial secretion systems and human proteins. Existing databases are incomplete, lacking annotations, including the display of protein 3D structures, as well as the presentation of their interaction interfaces and functional sites. Here we introduce a comprehensive platform for the interaction between bacterial secreted proteins and human proteins. This platform contains data resources for the interaction between secretion system effectors (TxSEs) from ten bacterial secretion systems and human proteins. It provides experimentally validated Protein-Protein Interactions (PPIs), 3D complex structures of protein interactions, as well as displays of the interaction interfaces and functional sites of PPIs. Additionally, we will continuously update predicted PPIs in the future.