Section “Fundamental and applied 3D genomics”

The central questions of the section “Fundamental and applied 3D genomics” of the symposium “Genomics, transcriptomics and bioinformatics” include:

• new bioinformatics methods for reconstruction of the spatial organization of chromatin (including using machine learning);
• mechanisms of chromatin folding and their significance for regulation of transcription, repair of DNA damage, cell division, formation and maintenance of mechanical properties of the cell nucleus,
• features of the evolution of the spatial organization of chromatin, etc.
• In addition to fundamental questions, applied and methodological aspects of 3D genomics are encouraged for the discussion.
• An important topic of the section is the use of chromosome conformation capture technologies in medical genetic studies and for the purpose of genome assembly and annotation.