Accepted_test

Metabolic modeling of the production of a recombinant protein by methanotrophs

by Kulyashov Mikhail | Department of Computational Biology, Scientific Center for Genetics and Life Sciences, Sirius University of Science and Technology, Sirius, Russia

Abstract ID: 627

Event: BGRS-abstracts

Sections: [Sym 8] Modeling and computer analysis of microbiological systems and processes

Methanotrophic bacteria are widely used in advanced biotechnology, beginning from the production of single cell protein (SCP), and ending with different cell metabolites: succinate, polyhydroxyalkanoates (PHAs), ectoine, methanol and others. Main advantage of their application in biotechnology is using a low-cost and available source - methane. One of these organisms widely studied among methanotrophs is Methylotuvimicrobium alcaliphilum 20ZR, for which the production of recombinant proteins is the new biotechnology field of its application in a few last year’s. Moreover, a genome-scale metabolic (GSM) model verified by a few omics experimental datasets was developed for the strain.