Accepted_test

Nonverbal intelligence is a person's ability to understand and use information presented in the form of images, graphs, diagrams, and other visual elements, without the need to use words. This type of intelligence plays an important role in various fields of life, such as mathematics, geography, physics, computer science and many others. This study presents the results of a genome-wide association studies with the level of nonverbal intelligence in populations from the Volga-Ural region. The study was conducted on a sample of mentally healthy students of higher educational institutions of the Russian Federation (N = 1422, 80% were women; age 18-25 years). The level of nonverbal intelligence was assessed using the Internet version of the Raven's Progressive Matrices questionnaire. Genotyping was performed using the Infinium Global Screening Array v3.0 kit from Illumina (USA). Statistical analysis and assessment of genotyping quality were performed using Plink v 1.09 and the R. As a result of the study, it was shown that genes regulating the immune system (rs35647108 (p = 2.1*10^-6), rs7745906 (p = 4.8*10^-6), rs6908994 (p = 5.0*10^-6), rs9295957 (p = 6.8*10^-6), rs28360058 (p = 7.3*10^-6), localized close to the genes HLA-B, HLA-C), cell energy metabolism (rs9323788 (p = 3.5*10^-5) and rs28381984 (p = 3.5*10^-5) in the MFF gene), and neurogenesis (rs757911 (p = 3.1*10^-5) in the GLI3 gene) are involved in the formation of the level of nonverbal intelligence.