Accepted_test

Introduction of nucleic acids into scaffolds: manufacturing, study of the properties and efficiency of cell transfection

Authors:
Chernonosova Vera, Institute of Chemical Biology and Fundamental Medicine, SB RAS
Khlebnikova M, Institute of Chemical Biology and Fundamental Medicine, SB RAS
Popova V, Institute of Chemical Biology and Fundamental Medicine, SB RAS
Chelobanov B, Institute of Chemical Biology and Fundamental Medicine, SB RAS
Kiseleva E, Institute of Cytology and Genetics, SB RAS
Laktionov P, Institute of Chemical Biology and Fundamental Medicine, SB RAS

Abstract ID: 701

Event: BGRS-abstracts

Sections: [Sym 9] Section“Tissue engineering”

The engineering of a heterogeneous tissue usually requires a combination of biomaterials
with spatially organized material composition and signaling molecules for cells.
Given these requirements, electrospinning is considered a promising technology for the
production of tissue engineering devices. In the present study we demonstrated a strategy
for the incorporation of nanoparticle-associated pDNA—PEI supramolecular complexes
into electrospun nanofibers for localized gene transfection.