Accepted_test
Introduction of nucleic acids into scaffolds: manufacturing, study of the properties and efficiency of cell transfection
The engineering of a heterogeneous tissue usually requires a combination of biomaterials
with spatially organized material composition and signaling molecules for cells.
Given these requirements, electrospinning is considered a promising technology for the
production of tissue engineering devices. In the present study we demonstrated a strategy
for the incorporation of nanoparticle-associated pDNA—PEI supramolecular complexes
into electrospun nanofibers for localized gene transfection.