Accepted_test

Testing plink parameters to identify homozygosity sites
by Anna Korobeinikova | CSP FMBA
Abstract ID: 726
Event: BGRS-abstracts
Sections: [Sym 7] Section “Genomics, genetics and systems biology of animals”

To study the effect of autozygosity, there are many programmes that identify homozygous regions. The PLINK software is the most used of these. This algorithm is implemented using a sliding window technique that traverses the entire genome and gives an estimate of the proportion of each SNP in the homozygous window. As there is still no consensus in research studies about which parameters to consider universal in this analysis, there are problems with the accuracy of the results obtained and difficulties in comparing them between different studies. In this paper, we aim to test the parameters that contribute most to the variability of the results and to identify the best option that will ensure high reliability of the study.