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Molecular mechanisms of cell death under cold plasma jet ex-posure: potential enhancement with gold nanoparticles
Cold physical plasma (CP) is a new modality in cancer research that can help enhance the results of chemotherapy and immunotherapy. The result of plasma interaction with biological object is the generation of ions, oxygen- and nitrogen-related species (RONS) in the gas and water environment that actively react with the cells of biological tissue, causing cell death under certain irradiation regimes. The sensitivity of various healthy and tumor cells to plasma irradiation has been shown to be different. Therefore, the study of the mechanisms of resistance of grown human cells to the cold plasma jet of atmospheric pressure and the search for overcoming such resistance is an urgent task of plasma medicine.