Results of whole-genome sequencing and phenotype annotation of bacteria of the genus Listeria

The incidence of listeriosis in recent years is con- stantly increasing. So, in highly developed countries it ranges from 0.3 to 1.5%, while in Russia – only 0.04% [1]. Moreover, the indicators in Moscow and St. Petersburg exceed those in the whole country by 4 times, which is explained by the different quality of clinical and laboratory diagnostics. Moreover, mortality due to complications of listeriosis infection can reach 30% [2]. Therefore, the fact of contamination of food products with listeria is of great concern. In this case, the strains of the species L. monocytogenes, L. innocua, L. ivanovii, L. grayii, L. seeligeri, L. welshimeri are most often distinguished. And if earlier it was believed that representatives of the species L. monocytogenespossess the largest set of pathogenic factors, then the possibilities of molecular and bioinformatics research methods provide a reliable picture with respect to other representatives of the genusListeria, in particular L. innocua.