The first insights into regulation of cell transdifferentiation during gut regeneration in Eupentacta fraudatrix

Alexey Boyko¹, Igor Dolmatov^2
1NSCMB FEB RAS, Vladivostok, Russia, Alteroldis@gmail.com
²NSCMB FEB RAS, Vladivostok, Russia, idolmatov@mail.ru

The holothurian Eupentacta fraudatrix is a unique organism for studying regeneration mechanisms. It has been repeatedly confirmed that regeneration is only due to the transformation of terminally differentiated cells. In this study, we examined changes in gene expression during gut regeneration of the holothurian E. fraudatrix and found 11 TFs, which are candidates for the role of transdifferentiation regulators.