Loci and genes involved in chronic musculoskeletal pain identified via analysis of genetically independent pain phenotypes

Yakov Tsepilov1, Maxim B. Freidin2, Alexandra S. Shadrina3, Sodbo Z. Sharapov4, Elizaveta E. Elgaeva5, Jan van Zundert6, Lennart РЎ. Karssen7, Pradeep Suri8, Frances M.K. Williams9, Yurii S. Aulchenko10
1Novosibirsk State University, drosophila.simulans@gmail.com
2King’s College London, maxim.freydin@kcl.ac.uk
3Novosibirsk State University, weiner.alexserg@gmail.com
4Novosibirsk State University, sharapovsodbo@gmail.com
5Novosibirsk State University, elizabeth.elgaeva@gmail.com
6Maastricht University Medical Centre, jan.vanzundert@zol.be
7PolyOmica, l.c.karssen@polyomica.com
8VA Puget Sound Health Care System, pradeepsuri1@gmail.com
9King’s College London, frances.williams@kcl.ac.uk
10Novosibirsk State University, y.s.aulchenko@polyomica.com

We have evaluated four genetically independent pain phenotypes of four common chronic musculoskeletal pains (GIPs). We assume that the first GIP represents a biopsychological component of chronic musculoskeletal pain, related to physiological and psychological aspects and possibly reflecting pain perception and processing.

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