OrthoWeb – web application for macro- and microevolutionary analysis of genes

Poster (download)

409

Zakhar Mustafin, Alexey Mukhin, Dmitry Afonnikov, Yury Matushkin, Sergey Lashin^1
1Kurchatov Genomics Center, ICG SB RAS, Novosibirsk, Russia, mustafinzs@bionet.nsc.ru

Problems of macro- and microevolution remain key problems of biology. Phylostratigraphic analysis became one of the most popular methods for studying macroevolutionary characteristic of genes. It is based on estimation of the divergence time among orthologous genes. Along with methods of microevolutionary analysis (for example, dN/dS ratio estimation), phylostratigraphic methods are increasingly included into the methodological arsenal of evolutionary bioinformatics. There are some software packages used for computational analysis of the evolution by using different phylostratigraphic and microevolutionary indices, but they require users to know some additional software or programming languages. Here we present OrthoWeb software to calculate such indices using web browser only.