Phylostratigraphic approach in evolutionary analysis: comparison of methods

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Tatiana Martusheva¹, Zakhar Mustafin², Sergey Lashin^3
1Novosibirsk State University, NSU, Novosibirsk, Russia, t.maryanovskaya@g.nsu.ru
²Kurchatov Genomics Center, ICG SB RAS, Novosibirsk, Russia, mustafinzs@bionet.nsc.ru
³Kurchatov Genomics Center, ICG SB RAS, Novosibirsk, Russia NSU, Novosibirsk, Russia, lashin@bionet.nsc.ru

Phylostratigraphic analysis allows us to determine the \”age of the gene\” – evolutionary time of its origin. There are different methods to calculate this age, each of which has its own issues. In this work, we compare several studies on phylostrastigraphic analysis. The correlation coefficient of the results of two research with different phylostratigraphic trees but the same method to count phylostratigraphic age (BLAST-based) was found to be 0.76. Comparison of the results of calculating the phylostratigraphic age by Orthoscape application (used KEGG as data source) and the myTAI package (used BLAST as data source) showed a lower corellation coefficient – only 0.27. It is planned to continue the studying of differences in the results of different methods and their reasons.