Predicting elongation efficiency of gene translation for annotation of bacterial genomes: a case study for biosynthetic gene clusters of nonribosomal peptides

Poster (download) A.I. Klimenko1, Yu.G. Matushkin2, D.A. Afonnikov31Kurchatov Genomics Center, Institute of Cytology and Genetics, klimenko@bionet.nsc.ru2ICG SB RAS, mat@bionet.nsc.ru3ICG SB RAS, NSU, ada@bonet.nsc.ru The gene expression levels for bacteria are largely determined by the efficiency of translation elongation. We have performed bioinformatic elongation efficiency analysis of NRP biosynthetic gene clusters (BGCs) obtained from ANTISMASH-DB using whole-genome sequences of bacterial genomes that are available at NCBI Genbank. The analysis has provided the information about distribution of nonribosomal peptide biosynthetic gene clusters in bacteria and their putative translation elongation efficiency.

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Hemolymph metagenome of endemic amphipod Eulimnogammarus verrucosus from Lake Baikal

Poster (download) Ekaterina Shchapova11Irkutsk State University, shchapova.katerina@gmail.com A diverse number of studies indicates that the hemolymph of aquatic invertebrates, apparently healthy invertebrates, is non-sterile. In this study we for the first time characterized the bacterial diversity in hemolymph of endemic amphipods from Lake Baikal on the example of abundant littoral species Eulimnogammarus verrucosus.

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