immunoglobulins

Poster (download) Video (download) Evgeny Ermakov1, Valentina Buneva2, Georgy Nevinsky31ICBFM SB RAS, Novosibirsk, Russia; NSU, Novosibirsk, Russia, evgeny_ermakov@mail.ru2ICBFM SB RAS, Novosibirsk, Russia; NSU, Novosibirsk, Russia, buneva@niboch.nsc.ru3ICBFM SB RAS, Novosibirsk, Russia; NSU, Novosibirsk, Russia, nevinsky@niboch.nsc.com Schizophrenia is known to be associated not only with imbalance in the neurotransmitter systems but also with immune system dysregulation. In this work, we found that pure polyclonal IgG preparations of patients with schizophrenia possess histone hydrolyzing proteolytic activity. The presence of proteolytic activity of IgGs is evidence of impaired humoral immune system in schizophrenia, which can be used as a biomarker for immunophenotyping of patients.

Immunoglobulins with proteolytic activity as a biomarker of impaired humoral immune system in schizophrenia

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Melatonin as a key regulator in molecular-genetic network of glucose variability related to circadian rhythm

THE EFFECT OF THE MELATONIN-CONTAINING PREPARATION ON THE HISTOLOGICAL STRUCTURE OF THE ORGANS OF THE IMMUNE SYSTEM OF MICE UNDER ROUND-THE-CLOCK ILLUMINATION

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