A new method for combining of genetically correlated traits by maximizing of their shared heritability

Video (download) Gulnara R. Svishcheva1, Evgeny S. Tiys2, Sofya G. Feoktistova3, Elizaveta E. Elgaeva4, Sodbo Sharapov5, Yakov A. Tsepilov61Institute of cytology and genetics, gulsvi@mail.ru2Institute of cytology and genetics, tiys@bionet.nsc.ru3Institute of cytology and genetics, sayfutdinovas@gmail.com4Institute of cytology and genetics, elizabeth.elgaeva@gmail.com5Institute of cytology and genetics, sharapovsodbo@gmail.com6Novosibirsk State University, drosophila.simulans@gmail.com Genetic correlations between phenotypic traits are widely observed phenomena. Many groups of traits have a significant level of shared genetic background. In this work, we suggested a new method for extraction of shared genetic component for genetically correlated phenotypic traits. We applied the method to GWAS results for anthropometric traits.

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