Zulfiia Guvatova1, George Krasnov2, Sergey Simanovsky3, Alexander Frolov4, Nataliya Gladysh5, Anna Kudryavtseva61Center for Precision Genome Editing and Genetic Technologies for Biomedicine Engelhardt Institute of Molecular Biology, Russian Academy of Sciences Moscow, Russia, guvatova.zulfiya@mail.ru2Center for Precision Genome Editing and Genetic Technologies for Biomedicine Engelhardt Institute of Molecular Biology, Russian Academy of Sciences Moscow, Russia, gskrasnov@mail.ru3Laboratory for Ecological Monitoring of Nuclear Power Plant (NPP) Regions and Bioindication Russia A.N. Severtsov Institute of Ecology and Evolution Moscow, Russia, sergey.a.simanovsky@gmail.com4Laboratory for Ecological Monitoring of Nuclear Power Plant (NPP) Regions and Bioindication Russia A.N. Severtsov Institute of Ecology and Evolution Moscow, Russia, frolov@mail.ru5Veterinary biology faculty MSAVM&B – MVA named after K.I. Skryabin Moscow, Russia, natalyagladish@gmail.com6Center for Precision Genome Editing and Genetic Technologies for Biomedicine Engelhardt Institute of Molecular Biology, Russian Academy of Sciences Moscow, Russia, rhizamoeba@mail.ru Annual fishes of the genus Nothobranchius from East Africa are promising vertebrate model in comparative and ageing studies. Nothobranchius show accelerated growth and age-related changes at all levels of organization. The present work aims to compare brain transcriptome profiles of short-lived N. rachovii with longer-lived N. korthausae and N. guntheri.

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