Poster (download) Alexander Lykov1, Lubov Rachkovskaya2, Olga Poveshchenko3, Maria Surovtseva4, Irina Kim5, Edmund Rachkovsky6, Maxim Korolev7, Ruslan Gevorgiz8, Svetlana Zheleznova9, Anastasiya Kotlyarova10, Andrey Letyagin111Research Institute of Clinical ans Experimental Lymphology- Branch of the Institute of Cytology and Genetics SB RAS, aplykov2@mail.ru2Research Institute of Clinical ans Experimental Lymphology- Branch of the Institute of Cytology and Genetics SB RAS, lymphology@niikel.ru3Research Institute of Clinical ans Experimental Lymphology- Branch of the Institute of Cytology and Genetics SB RAS, poveschenkoov@yandex.ru4Research Institute of Clinical ans Experimental Lymphology- Branch of the Institute of Cytology and Genetics SB RAS, mfelde@ngs.ru5Research Institute of Clinical ans Experimental Lymphology- Branch of the Institute of Cytology and Genetics SB RAS, kii5@yandex.ru6Research Institute of Clinical ans Experimental Lymphology- Branch of the Institute of Cytology and Genetics SB RAS, lymphology@niikel.ru7Research Institute of Clinical ans Experimental Lymphology- Branch of the Institute of Cytology and Genetics SB RAS, kormax@bk.ru8A.O. Kovalevsky Institute of Biology of the Southern Seas RAS, r.gevorgiz@yandex.ru9A.O. Kovalevsky Institute of Biology of the Southern Seas RAS, zheleznovasveta@yandex.ru10Research Institute of Clinical ans Experimental Lymphology- Branch of the Institute of Cytology and Genetics SB RAS, kotlyarova.anastasiya@yandex.ru11Research Institute of Clinical ans Experimental Lymphology- Branch of the Institute of Cytology and Genetics SB RAS, letyaginay@bionet.nsc.ru This work described toxicity of composition of fucoxanthin with particles of porous aluminum oxide with polydimethylsiloxane (Fx@Al/PDMS) in mice lymphocytes. Effects of Fx@Al/PDMS on Balb/c mice splenocytes and thymocytes viability, and proliferation, and intracellular myeloperoxidase activity, and nitric oxide (NO) production, and apoptosis were studied. It was shown that short-term (24 h) and long-term (129 h) incubation lymphocytes with Fx@Al/PDMS did not have any adverse effect on functional properties of splenocytes and thymocytes.