Poster (download)
151
Video (download)
Kakurina G.V.1, Kolegova E.S2, Staheeva M.N.3, Cheremisina O.V.4, Kondakova I.V.5, Choynzonov E.L.6
1Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences Tomsk, Russia, kakurinagv@oncology.tomsk.ru
2Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences Tomsk, Russia, biochem@oncology.tomsk.ru
3Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences Tomsk, Russia, stakheyevam@oncology.tomsk.ru
4Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences Tomsk, Russia, onco@tnimc.ru
5Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences Tomsk, Russia, biochem@oncology.tomsk.ru
6Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences Tomsk, Russia, onco@tnimc.ru
To determine the markers of metastasis, it is important to study the molecular characteristics of tumor progression among patients with Squamous cell carcinoma of the larynx and larynxopharynx (L/L SCC). The aim of the study was to study the relationship between the level of actin binding proteins (ABS) (adenylyl cyclase-associated protein 1 (CAP1), cofilin 1, ezrin, fascin 1 and profilin 1) in the blood serum of patients with L/L SCC with the main clinical and morphological characteristics and to assess the possibility of their use as markers of metastasis. Several serum ABPs (CAP1, profilin1 and fascin 1) have been identified as potential markers of metastasis of L/L SCC. For the presented sample of patients a metastasis prognosis model was obtained. For further conclusions about the clinical value of the proposed metastasis markers, further studies with an expanding sample of patients are needed.
Thank you for your presentation. Let me ask you some questions. In your study Fascin level in the control group was higher than in patients with laryngeal cancer. At the same time, you are using increased fascin concentration as a marker of metastasis. Do you see a contradiction in this? Which of the markers is the most significant in your opinion?
1. A group of patients with metastases (T2-4N1-2M0) and without metastases (T2-4N0M0) was compared. this analysis did not include the T1N0M0 group.
2. possible tandem CFL1, PFN1, CAP1. need to conduct additional research
coffee jazz
warm jazz music
sleep music
yoga music
soft jazz instrumental
relaxing music
good mood jazz
soothing piano music
sleep meditation
coffee relaxing jazz
jazz music meaning
spa music
romantic bossa nova