Developing an accurate force field for simulating modified RNA

by Ansuman Lahiri | University of Calcutta Post-transcriptional modifications occur extensively in RNA and provide an additional layer of chemical coding that presumably alters the chemistry, structure and dynamics of the molecules. Molecular dynamics simulations offer a convenient tool to elucidate the mechanisms underlying the roles played by such modifications. However, since the reliability of […]

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Analysis of binding properties of influenza hemagglutinins and human receptor analog

by Vasily Unguryan | Novosibirsk State University, State Research Center of Virology and Biotechnology VECTOR Motivation and Aim: The surface protein of the influenza virus, hemagglutinin, plays a key role in the virus entry into the cell. When infecting a cell, the virus first binds to a receptor on the cell membrane surface, followed by […]

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