Re-analysis of DNA methylationin genes associated with bronchial asthma

by Babushkina Nadezhda | Bragina Elena | Gonchrova Irina | Markov Anton | Kucher Aksana | Babushkina Nadezhda | Nazarenko Maria | Research Institute of Medical Genetics, Tomsk National Research Medical Center RAS, Tomsk, Russia 

To study the variability of gene methylation patterns, which in our previous studies showed
associations with bronchial asthma and tuberculosis (which are dystrophic diseases), we reanalyzed two datasets GSE104471 and GSE59339 from the public repository of functional
genomic data Gene Expression Omnibus (GEO) [1]. The goal of the study was to compare
DNA methylation level associated with bronchial asthma genes in different groups..Type
here a short description of your report.
The data obtained as a result of reanalysis on differences in the level of DNA methylation of
a number of genes associated with bronchial asthma indicate the potential significance of
epigenetic modifications in predisposition to this pathology

BGRS-SB-2022-BA