Loci associated with negative heterosis for viability and meat productivity in interspecies sheep hybrids

by Alexander S. Zlobin | Natalia A. Volkova | Natalia A. Zinovieva | Baylar S. Iolchiev | Vugar A. Bagirov | Pavel M. Borodin | Tatiana I. Aksenovich | Yakov A. Tsepilov | Kurchatov Genomic Center of the Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia | L.K. Ernst Federal Science Center for Animal […]

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Domestication explains 2/3 of differential gene expression variance between domestic and wild animals; the remaining 1/3 reflects intraspecific and interspecific variation

by Chadaeva Irina | Ponomarenko P. | Kozhemyakina R. | Suslov V. | Bogomolov A. | Klimova N. | Shikhevich S. | Savinkova L. | Oshchepkov D. | Kolchanov N.A. | Markel A. | Ponomarenko M. | ICG SB RAS Here we sequenced hypothalamic transcriptomes of tame and aggressive rats, identified their differentially expressed genes […]

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Distribution of cell junction proteins in the descending colon of Muc2 mice

by Saydakova Snezhanna Sergeevna | Ogienko Anna Aleksandrovna | Boldyreva Lidia Valerievna | Kozhevnikova Elena Nikolaevna | Scientific Research Institute of Neurosciences and Medicine, Novosibirsk, Russia | Institute of Molecular and Cellular Biology, SB RAS, Novosibirsk, Russia | Scientific Research Institute of Neurosciences and Medicine, Novosibirsk, Russia | Scientific Research Institute of Neurosciences and Medicine, […]

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The effect of diol on behavior in a MPTP-induced model of Parkinson’s disease in mice

by Gild Emma-Yanina Vitalyevna | Tenditnik Mikhail Vladimirovich | Dubrovina Nina Ivanovna | Volcho Konstantin Petrovich | Salakhutdinov Nariman Faridovich | Amstislavskaya Tamara Gennadyevna | Tikhonova Maria Alexandrovna | Scientific Research Institute of Neurosciences and Medicine, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, Russia | Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Novosibirsk, Russia

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Oral trehalose intake as an experimental therapy for Alzheimer’s disease in a mouse model induced by the central administration of amyloid-β

by Alexander Pupyshev | Ph.D. Three regimens of trehalose application rendered high therapeutic effect in the treatment of acute pharmacomodel of Alzheimer’s disease caused by intraventricular injection of fragment of amyloid-beta 25-35. Mice of C57Bl/6 recieved 2 or 4 % trehalose solution (plus in intermittent mode) per os during 2 weeks as treatment. Activity of […]

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Production of fox FGF2 for fox pluripotent stem cell culture

by Aleksei Menzorov | Nikolay Meshcheryakov | Alexander Smirnov | Institute of Cytologe and Genetics SB RAS, Novosibirsk, Russia | Novosibirsk State University, Russia | Institute of Cytologe and Genetics SB RAS, Novosibirsk, Russia We have produced a cell line with fox FGF2 expression. The protein yield in the conditioned medium is low for the […]

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