Oral trehalose intake as an experimental therapy for Alzheimer’s disease in a mouse model induced by the central administration of amyloid-β

by Alexander Pupyshev | Ph.D. Three regimens of trehalose application rendered high therapeutic effect in the treatment of acute pharmacomodel of Alzheimer’s disease caused by intraventricular injection of fragment of amyloid-beta 25-35. Mice of C57Bl/6 recieved 2 or 4 % trehalose solution (plus in intermittent mode) per os during 2 weeks as treatment. Activity of […]

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